Sulforaphene efficiently decreased the viability of breast cancer cells, while normal cells (MCF10A) were less sensitive to the analyzed isothiocyanate. Sulforaphene induced G2/M cell cycle arrest, as well as disturbed cytoskeletal organization and reduced clonogenic potential of the cancer cells. Sulforaphene induced apoptosis in a concentration-dependent manner which was associated with the oxidative stress, mitochondria dysfunction, Bcl2 ratio and ADRP levels. References: Lee JG, Lim S, Kim J, Lee EJ. The mechanism of deterioration of the glucosinolate-myrosynase system in radish roots during cold storage after harvest. Food Chem. 2017 Oct 15;233:60-68. doi: 10.1016/j.foodchem.2017.04.104. Epub 2017 Apr 19. PubMed PMID: 28530612.

纯度：≥98%

CAS：592-95-0