Pemetrexed disodium heptahydrate (LY231514; HSDB7316; LY-231514; HSDB-7316; Alimta), the heptahydrated disodium salt of Pemetrexed and a pyrimidine-based antifolate, is an antifolate and antimetabolite anticancer medication. It acts by targeting TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively. Pemetrexed exhibits high autitumor activity in a broad range of tumors such as NSCLC/non-small cell lung carcinoma, malignant mesothelioma, and carcinomas of the breast, colorectum, uterine cervix, head and neck, and bladder.

纯度：≥98%

CAS：357166-29-1