DX-9065A is a factor Xa inhibitor potentially for the treatment of acute coronary syndromes, thrombosis and angina. DX-9065a inhibits proinflammatory events induced by gingipains and factor Xa. DX-9065a is a competitive inhibitor of the Spectrozyme FXa (SpFXa) cleavage by both fXa and prothrombinase with similar K(i) values of approximately 10-20 nM. References: Graff J, Picard-Willems B, Harder S. Monitoring effects of direct FXa-inhibitors with a new one-step prothrombinase-induced clotting time (PiCT) assay: comparative in vitro investigation with heparin, enoxaparin, fondaparinux and DX 9065a. Int J Clin Pharmacol Ther. 2007 Apr;45(4):237-43. PubMed PMID: 17474542.

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CAS：155204-81-2