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Ionomycin calcium(SQ23377
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ionomycin calcium(SQ23377图片
CAS NO:56092-82-1
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍

Description: Ionomycin calcium (SQ-23377; SQ23377), the calcium salt of Ionomycin, is a selective and potent Ca 2+ ionophore. It is an antibiotic and polyether isolated from Streptomyces conglobatus. Ionomycin (SQ23377) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin also induces the activation of protein kinase C (PKC). Its depletion of intracellular Ca 2+ stores may be linked to the induction of apoptosis.

References:

[1]. Liu C,et al. Characterization of ionomycin as a calcium ionophore. J Biol Chem. 1978 Sep 10;253(17):5892-4.

[2]. Chatila T, et al. Mechanisms of T cell activation by the calcium ionophore ionomycin. J Immunol. 1989 Aug 15;143(4):1283-9.

[3]. Gil-Parrado S, et al. Ionomycin-activated calpain triggers apoptosis. A probable role for Bcl-2 family members. J Biol Chem. 2002 Jul 26;277(30):27217-26.

Related CAS #: 56092-81-0 (free acid) 56092-82-1 (calcium)

纯度:≥98%

CAS:56092-82-1