SN00799639, formerly known as SN639, is a potent inhibitor of the motility and development of parasitic larvae of Haemonchus contortus, a blood-feeding parasitic nematode of major economic importance in ruminants. SN639 displayed lower potency, with IC50 of 8.4 μM (xL3 motility) and 0.29 μM (L4 development). References: Le T, Kundu A, Goshal A, Nguyen N, Preston S, Jiao Y, Ruan B, Xue L, Huang F, Keiser J, Hofmann A, Chang B, Garcia-Bustos J, Wells TNC, Palmer MJ, Jabbar A, Gasser RB, Baell JB. Novel 1-Methyl-1 Η-pyrazole-5-carboxamide Derivatives with Potent Anthelmintic Activity. J Med Chem. 2019 Mar 15. doi: 10.1021/acs.jmedchem.8b01790. [Epub ahead of print] PubMed PMID: 30875218.

纯度：≥98%

CAS：1340790-22-8