SL-017, formerly known as ACP-SL-017; ACPSL-017; ACP-SL-017, is a Hypocrellin-B (HB) analogue and photosensitiser potentially for the treatment of hair growth abnormality. SL017 treatment resulted in increased mitochondrial fragmentation which followed loss of ΔΨm. SL017 targets mitochondria, triggering collapse of mitochondrial membrane potential, generates ROS and subsequently results in mitochondrial fragmentation. References: El-Sikhry HE, Miller GG, Madiyalakan MR, Seubert JM. Sonodynamic and photodynamic mechanisms of action of the novel hypocrellin sonosensitizer, SL017: mitochondrial cell death is attenuated by 11, 12-epoxyeicosatrienoic acid. Invest New Drugs. 2011 Dec;29(6):1328-36. doi: 10.1007/s10637-010-9495-2. Epub 2010 Jul 30. PubMed PMID: 20676746.

纯度：≥98%

CAS：1169831-01-9