VU0359595 (ML-270, CID-53361951) is a novel and potent inhibitor of PLD1 (Phospholipase D1) with IC50 of 3.7 nM. Downregulation of PLD1 and exposure to the PLD1 inhibitor VU0359595 attenuated PLD activity and strongly reduced the mitogenic activity of serum and IGF-1. Phospholipase D is a target for inhibition of astroglial proliferation by ethanol.

纯度：≥98%

CAS：1246303-14-9