SKF-83959 HBr is a dopamine D1-like receptor partial agonist (Kis are 1.18, 7.56, 920 and 399 nM for rat D1, D5, D2 and D3 receptors respectively). SKF-83959 HBr may act as an antagonist in vivo, producing anti-Parkinsonian effects and antagonizing the behaviorally bioavailable effects of cocaine. References: Lee SM, Kant A, Blake D, Murthy V, Boyd K, Wyrick SJ, Mailman RB. SKF-83959 is not a highly-biased functionally selective D1 dopamine receptor ligand with activity at phospholipase C. Neuropharmacology. 2014 Nov;86:145-54. doi: 10.1016/j.neuropharm.2014.05.042. Epub 2014 Jun 12. PubMed PMID: 24929112; PubMed Central PMCID: PMC4188748.

纯度：≥98%

CAS：67287-95-0