SKF-107457 is a HIV protease type 1 inhibitor, and are hexapeptide substrate analogues with the scissile bond being replaced by a hydroxyethylene isostere. References: Murthy KH, Winborne EL, Minnich MD, Culp JS, Debouck C. The crystal structures at 2.2-A resolution of hydroxyethylene-based inhibitors bound to human immunodeficiency virus type 1 protease show that the inhibitors are present in two distinct orientations. J Biol Chem. 1992 Nov 15;267(32):22770-8. PubMed PMID: 1429626.

纯度：≥98%

CAS：126333-28-6