ITX3 is a nontoxic selective cell active inhibitor of the Trio/RhoG/Rac1 pathway. It acts by validating RhoGEFs as druggable targets. References: Son K, Smith TC, Luna EJ. Supervillin binds the Rac/Rho-GEF Trio and increases Trio-mediated Rac1 activation. Cytoskeleton (Hoboken). 2015 Jan;72(1):47-64. doi: 10.1002/cm.21210. Epub 2015 Feb 28. PubMed PMID: 25655724; PubMed Central PMCID: PMC4361246.

纯度：≥98%

CAS：347323-96-0