JNJ-26146900 is a nonsteroidal androgen receptor (AR) ligand with tissue-selective activity in rats. It binds to the rat AR with a K(i) of 400nM and acts as a pure androgen antagonist in an in vitro cell-based assay. JNJ-26146900 has the potential for anabolic effects on bone and muscle while maintaining therapeutic efficacy in prostate cancer. References: Allan G, Lai MT, Sbriscia T, Linton O, Haynes-Johnson D, Bhattacharjee S, Dodds R, Fiordeliso J, Lanter J, Sui Z, Lundeen S. A selective androgen receptor

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CAS：868691-50-3