Shikonin is a natural product from the root of Lithospermum erythrorhizon and a specific inhibitor of pyruvate kinase M2 (PKM2). Shikonin also suppresses the ATF2 pathway in skin carcinogenesis. References: Andújar I, Ríos JL, Giner RM, Recio MC. Pharmacological properties of shikonin - a review of literature since 2002. Planta Med. 2013 Dec;79(18):1685-97. doi: 10.1055/s-0033-1350934. Epub 2013 Oct 23. Review. PubMed PMID: 24155261.

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CAS：517-89-5