JNJ-40413269 is a competitive inhibitor of fatty acid amide hydrolase (FAAH), which displays robust central target engagement, and shows efficacious in a rat model of neuropathic pain. References: Keith JM, Hawryluk N, Apodaca RL, Chambers A, Pierce JM, Seierstad M, Palmer JA, Webb M, Karbarz MJ, Scott BP, Wilson SJ, Luo L, Wennerholm ML, Chang L, Rizzolio M, Chaplan SR, Breitenbucher JG. 1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase. Bioorg Med Chem Lett. 2014 Mar 1;24(5):1280-4. doi: 10.1016/j.bmcl.2014.01.064. Epub 2014 Jan 31. PubMed PMID: 24513048.

纯度：≥98%

CAS：1184847-16-2