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重组鸟嘌呤核苷酸交换因子4蛋白
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
Recombinant RAPGEF4
Recombinant Rap guanine nucleotide exchange factor 4 protein
产品介绍
基因名:

RAPGEF4


产品别名:

CAMP-GEFII; CGEF2; EPAC; EPAC 2; EPAC2; Nbla00496; RAPGEF4; Rap guanine nucleotide exchange factor 4; Rap guanine nucleotide exchange factor 4; rap guanine nucleotide exchange factor 4; RAP guanine-nucleotide-exchange factor (GEF) 4; Rap guanine nucleotide exchange factor (GEF) 4; cAMP-regulated guanine nucleotide exchange factor II; exchange factor directly activated by cAMP 2; exchange protein directly activated by cAMP 2; putative protein product of Nbla00496; 鸟嘌呤核苷酸交换因子4;


背景信息:
3',5' cyclic adenosine monophosphate (cAMP)-regulated guanine nucleotide exchange factors Epac1 (cAMP-GEFI) and Epac2 (cAMP-GEFII) activate the ras family GTPases Rap1 and Rap2 by promoting GTP binding in a cAMP-dependent manner (1,2). Eukaryotic cAMP is a second messenger that induces physiological responses such as gene expression, growth, differentiation, secretion and neurotransmission (3). Human EPAC2 contains at least 31 exons and maps to chromosome 2q31 (4). The 4.4-kb Epac2 transcript is prominent in brain and adrenal gland (5,6). Within the brain, expression is strong in cortex, occipital pole, frontal lobe, temporal lobe, amygdala, putamen, hippocampus and cerebellum (5,6).

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。