JWH 018 is a synthetic cannabinoid (CB) that potently activates the central CB1 and peripheral CB2 receptors (Ki = 9.0 and 2.94 nM, respectively). This cannabimimetic compound has frequently been found in herbal blends. JWH 424 is an 8-bromonaphthyl analogue of JWH 018 which shows a reduced selectivity for CB1 over CB2 (Ki = 20.9 and 5.4 nM, respectively). References: Tang J, Tao Y, Tan L, Yang L, Niu Y, Chen Q, Yang Y, Feng H, Chen Z, Zhu G. Cannabinoid receptor 2 attenuates microglial accumulation and brain injury following germinal matrix hemorrhage via ERK dephosphorylation in vivo and in vitro. Neuropharmacology. 2015 Aug;95:424-33. doi: 10.1016/j.neuropharm.2015.04.028. Epub 2015 May 9. PubMed PMID: 25963415.

纯度：≥98%

CAS：1366068-04-3