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重组丝氨酸/苏氨酸蛋白激酶DCAMKL1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
重组双肾上腺皮质激素样激酶1(DCLK1)蛋白
Recombinant DCLK1
产品介绍
基因名:

DCLK1


产品别名:

CL1; CLICK1; DCAMKL1; DCDC3A; DCLK; DCLK1; doublecortin like kinase 1; doublecortin like kinase 1; serine/threonine-protein kinase DCLK1; doublecortin domain-containing protein 3A; doublecortin-like and CAM kinase-like 1; 丝氨酸/苏氨酸蛋白激酶DCAMKL1; 双肾上腺皮质激素样激酶1(DCLK1);


背景信息:
Lissencephaly (smooth brain) is an abnormality of brain development characterized by incomplete neuronal migration and a smooth cerebral surface, manifesting as severe mental retardation. Genetic analysis has identified two proteins that are mutated in some cases of lissencephaly, designated lissencephaly-1 protein (LIS1) and doublecortin. LIS1 displays sequence homology to ?subunits of heterotrimeric G proteins, and doublecortin contains a consensus Abl phosphorylation site. In addition, the DCAMKL1 (doublecortin-like and CAM kinase-like 1) protein shows homology to doublecortin. All three proteins are highly expressed in developing brain and may function together to regulate microtubules involved in neuronal migration. The DCAMKL1 protein encodes a functional kinase that is capable of phosphorylating myelin basic protein and itself, but its kinase activity does not appear to affect its microtubule polymerization activity.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。