重组有丝分裂蛋白BUB3

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重组有丝分裂蛋白BUB3

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称

Recombinant BUB3
Recombinant BUB3 mitotic checkpoint protein

产品介绍

基因名：

BUB3

产品别名：

BUB3L； hBUB3； BUB3； BUB3 mitotic checkpoint protein； BUB3 mitotic checkpoint protein； mitotic checkpoint protein BUB3； BUB3 budding uninhibited by benzimidazoles 3 homolog； budding uninhibited by benomyl； budding uninhibited by benzimidazoles 3 homolog； mitotic checkpoint component； testicular tissue protein Li 27；有丝分裂蛋白BUB3；

背景信息：

Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。