重组DR4蛋白

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重组DR4蛋白

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称

重组DR5蛋白
Recombinant TNFRSF10B

产品介绍

基因名：

TNFRSF10B

产品别名：

CD262； DR5； KILLER； KILLER/DR5； TRAIL-R2； TRAILR2； TRICK2； TRICK2A； TRICK2B； TRICKB； ZTNFR9； TNFRSF10B； TNF receptor superfamily member 10b； TNF receptor superfamily member 10b； tumor necrosis factor receptor superfamily member 10B； Fas-like protein； TNF-related apoptosis-inducing ligand receptor 2； apoptosis inducing protein TRICK2A/2B； apoptosis inducing receptor TRAIL-R2； cytotoxic TRAIL receptor-2； death domain containing receptor for TRAIL/Apo-2L； death receptor 5； p53-regulated DNA damage-inducible cell death receptor(killer)； tumor necrosis factor receptor superfamily, member 10b； tumor necrosis factor receptor-like protein ZTNFR9； DR4蛋白； DR5蛋白；死亡受体5；死亡受体5(DR5)；肿瘤细胞调亡素/死亡受体5；

背景信息：

TNFRSF10B is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. The adapter molecule FADD recruits caspase-8 to the activated receptor and is required for the apoptosis mediated by TNFRSF10B. TNFRSF10B is expressed in a number of cell types, and to particularly high levels in lymphocytes and spleen. This single-pass transmembrane protein contains two cysteine-rich repeat units in its extracellular region, followed by a transmembrane segment and a cytoplasmic tail containing a typical 'death domain'. TNFRSF10B expression is regulated by the tumor suppressor p53. It is also indicated that the activation of NF-kappa-B can be promoted by TNFRSF10B.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。