生物活性
IB-MECA已被证明是一种有效的选择性腺苷A3-R激动剂,腺苷A3-R,腺苷A1-R和腺苷A2A-R的Ki值分别为1.1、54和56 nM。
化学数据
目录号 | A14345 |
作用机制 | Agonist (激动剂) |
M. Wt | 510.29 |
Formula | C18H19IN6O4 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
CAS No. | 152918-18-8 |
Synonyms | CF 101, IB-MECA |
SMILES | CNC(=O)[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C2N=CN=C3NCC4=CC(=CC=C4)I)O)O |
储备液配制
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
0.1 mM | 19.6 mL | 97.98 mL | 195.97 mL |
0.5 mM | 3.92 mL | 19.6 mL | 39.19 mL |
1 mM | 1.96 mL | 9.8 mL | 19.6 mL |
5 mM | 0.39 mL | 1.96 mL | 3.92 mL |
*The above data is based on the productmolecular weight 510.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.