KAR5417 is a potent and selective tryptophan hydroxylase-1 (TPH1) inhibitor. References: Goldberg DR, De Lombaert S, Aiello R, Bourassa P, Barucci N, Zhang Q, Paralkar V, Stein AJ, Holt M, Valentine J, Zavadoski W. Optimization of spirocyclic proline tryptophan hydroxylase-1 inhibitors. Bioorg Med Chem Lett. 2017 Feb 1;27(3):413-419. doi: 10.1016/j.bmcl.2016.12.053. Epub 2016 Dec 23. PubMed PMID: 28041831.

纯度：≥98%

CAS：1673568-73-4