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重组3磷酸肌醇依赖性蛋白激酶1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
重组磷酸化3磷酸肌醇依赖性蛋白激酶1
Recombinant PDPK1
产品介绍
基因名:

PDPK1


产品别名:

PDK1; PDPK2; PDPK2P; PRO0461; PDPK1; 3-phosphoinositide dependent protein kinase 1; 3-phosphoinositide dependent protein kinase 1; 3-phosphoinositide-dependent protein kinase 1; 3-phosphoinositide-dependent protein kinase 2 pseudogene; PkB kinase like gene 1; Putative 3-phosphoinositide-dependent protein kinase 2; 3磷酸肌醇依赖性蛋白激酶1; 磷酸化3磷酸肌醇依赖性蛋白激酶1; 磷酸肌醇依赖性蛋白激酶1(PDPK1);


背景信息:
PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。