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重组MDM2样P53蛋白结合
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
重组磷酸化MDM2样P53结合蛋白
Recombinant MDM4
产品介绍
基因名:

MDM4


产品别名:

BMFS6; HDMX; MDMX; MRP1; MDM4; MDM4 regulator of p53; MDM4 regulator of p53; protein Mdm4; MDM4, p53 regulator; MDM4-related protein 1; Mdm4 p53 binding protein homolog; double minute 4, human homolog of; p53-binding protein; mdm2-like p53-binding protein; protein Mdmx; MDM2样P53蛋白结合; 磷酸化MDM2样P53结合蛋白;


背景信息:
Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.Region I is sufficient for binding TP53 and inhibiting its G1 arrest and apoptosis functions. It also binds TP73. Region II contains most of a central acidic region and a putative C4-type zinc finger. The RING finger domain which coordinates two molecules of zinc mediates the heterooligomerization with MDM2.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。