KME 4 is an anti-inflammatory compound that has been shown to inhibit 5-lipoxygenase activity in both the cytosol and ionophore A23187-stimulated cells of guinea pig peritoneal polymorphonuclear leukocytes. References: Hidaka T, Takeo K, Hosoe K, Katsumi I, Yamashita T, Watanabe K. Inhibition of polymorphonuclear leukocyte 5-lipoxygenase and platelet cyclooxygenase by alpha-(3,5-di-tert-butyl-4-hydroxybenzylidene)-gamma-butyrolacto ne (KME-4), a new anti-inflammatory drug. Jpn J Pharmacol. 1985 Jul;38(3):267-72. PubMed PMID: 3932730.

纯度：≥98%

CAS：83677-24-1