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重组Disabled同源物2(DAB2)蛋白
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
重组信号转导功能磷蛋白DAB2
Recombinant DAB2
产品介绍
基因名:

DAB2


产品别名:

DOC-2; DOC2; DAB2; DAB adaptor protein 2; DAB adaptor protein 2; disabled homolog 2; DAB2, clathrin adaptor protein; Dab, mitogen-responsive phosphoprotein, homolog 2; adaptor molecule disabled-2; differentially expressed in ovarian carcinoma 2; differentially-expressed protein 2; disabled homolog 2, mitogen-responsive phosphoprotein; Disabled同源物2(DAB2); 信号转导功能磷蛋白DAB2; 磷酸化信号转导功能磷蛋白DAB2;


背景信息:
This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。