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重组细胞色素P450 2D6蛋白
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称
重组细胞色素P450家族成员2D6(CYP2D6)蛋白
Recombinant CYP2D6
产品介绍
基因名：

CYP2D6


产品别名：

CPD6； CYP2D； CYP2D7AP； CYP2D7BP； CYP2D7P2； CYP2D8P2； CYP2DL1； CYPIID6； P450-DB1； P450C2D； P450DB1； CYP2D6； cytochrome P450 family 2 subfamily D member 6； cytochrome P450 family 2 subfamily D member 6； cytochrome P450 2D6； cholesterol 25-hydroxylase； cytochrome P450, family 2, subfamily D, polypeptide 6； cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2； cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2； cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2； cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2； cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6； cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1； cytochrome P450-DB1； debrisoquine 4-hydroxylase； flavoprotein-linked monooxygenase； microsomal monooxygenase； nonfunctional cytochrome P450 2D6； xenobiotic monooxygenase； 细胞色素P450 2D6； 细胞色素P450家族成员2D6(CYP2D6)；


背景信息：
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 25% of commonly prescribed drugs. Its substrates include antidepressants, antipsychotics, analgesics and antitussives, beta adrenergic blocking agents, antiarrythmics and antiemetics. The gene is highly polymorphic in the human population; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. Some individuals with the poor metabolizer phenotype have no functional protein since they carry 2 null alleles whereas in other individuals the gene is absent. This gene can vary in copy number and individuals with the ultrarapid metabolizer phenotype can have 3 or more active copies of the gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014].

标签：His-tag   
分类：Recombinant  
类型：Protein   
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。