重组NADPH氧化酶2蛋白

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重组NADPH氧化酶2蛋白

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称

重组细胞色素b-245β肽(CYBb)蛋白
Recombinant CYBB

产品介绍

基因名：

CYBB

产品别名：

AMCBX2； CGD； CGDX； GP91-1； GP91-PHOX； GP91PHOX； IMD34； NOX2； p91-PHOX； CYBB； cytochrome b-245 beta chain； cytochrome b-245 beta chain； cytochrome b-245 heavy chain； CGD91-phox； NADPH oxidase 2； cytochrome b(558) subunit beta； cytochrome b-245 beta polypeptide； cytochrome b558 subunit beta； heme-binding membrane glycoprotein gp91phox； neutrophil cytochrome b 91 kDa polypeptide； p22 phagocyte B-cytochrome； superoxide-generating NADPH oxidase heavy chain subunit； NADPH氧化酶2；细胞色素b-245β肽(CYBb)；

背景信息：

NOX2/gp91phox is a critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. It also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc. Defects in CYBB are a cause of X-linked chronic granulomatous disease (X-CGD). X-CGD is characterized by the failure of activated phagocytes to generate superoxide. Patients suffer from life-threatening bacterial/fungal infections.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。