KRH-594, formerly known as WK-1492; WK-14922K, is a potent, specific and insurmountable AT1 receptor antagonist. KRH-594 prevents end-organ damage in stroke-prone spontaneously hypertensive/Izm rats. KRH-594 ameliorates nephropathy and hyperlipidaemia in diabetic spontaneously hypertensive rats. References: Komiyama J, Yang XP, Chiba S. Prejunctional AT(1) receptor subtype-dependent modification of neurotransmitter releases in canine isolated splenic arteries. Auton Autacoid Pharmacol. 2003 Oct-Dec;23(5-6):297-305. PubMed PMID: 15255814.

纯度：≥98%

CAS：167006-13-5