基因名：
ALAS2
产品别名：
ALAS-E； ALASE； ANH1； ASB； SIDBA1； XLDPP； XLEPP； XLSA； ALAS2； 5'-aminolevulinate synthase 2； 5'-aminolevulinate synthase 2； 5-aminolevulinate synthase, erythroid-specific, mitochondrial； 5-aminolevulinic acid synthase 2； aminolevulinate, delta-, synthase 2； delta-ALA synthase 2； delta-ALA synthetase； delta-aminolevulinate synthase 2； erythroid-specific delta-aminolevulinate synthase； 5-氨基乙酰丙酸合酶1； 氨乙酰丙酸δ合酶2(ALAS2)；
背景信息：
5-aminolevulinate synthase 1 (ALAS-H) and 2 (ALAS-E) are two isoforms of ALAS, an enzyme catalyzing the first step of the heme biosynthetic pathway in mammals. The erythroid-specific isoenzyme, ALAS-E, regulates the first step of hematopoietic cell differentation and iron metabolism in the liver. ALAS-H is a housekeeping protein which mediates synthesis of early heme in the mitochondria of most cells. Succinyl CoA associates with ALAS-E in protein conformation change and translocation of ALAS-E into the mitochondria and does not interact with ALAS-H. The ALAS-E 5'-flanking region contains binding sites for nuclear activators such as GATA-1, NF-E2 and EKLF. Since the ALAS gene maps to the X chromosome, mutation of the gene leads to the pyridoxine-refractory X-linked sideroblastic anemia.
标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
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