L 689502 is a potent inhibitor of HIV-l protease with an IC50 of 1 nM. IC50 & 1 nM (HIV-l protease) Both L694746 and L-689502 inhibit HIV-l ptotease activity in a concentration-dependent manner. Pepstatin is much less potent than either compound exhibiting an IC50 of 2 μM. L694746 is as potent as L-689502 in inhibiting the HIV-l protease despite being structurally different from L-689502. References: Vieth M, Cummins DJ. DoMCoSAR: a novel approach for establishing the docking mode that is consistent with the structure-activity relationship. Application to HIV-1 protease inhibitors and VEGF receptor tyrosine kinase inhibitors. J Med Chem. 2000 Aug 10;43(16):3020-32. PubMed PMID: 10956210.

纯度：≥98%

CAS：138483-63-3