The SLC35 family of nucleotide sugar transporters link the synthesis of activated sugar molecules and sulfate in the cytoplasm, with the luminal transferases that catalyse their attachment to proteins and lipids during glycosylation and sulfation. SLC35G2 belongs to the SLC35G solute transporter family. SLC35G2 is located on human chromosome 3q22.3. The SLC35G2 (also known as TMEM22) protein is broadly expressed in adrenal, testis and other tissues. Structurally, the encoded protein is reported to be 46422 Da in mass. SLC35G2 may play a role in cell proliferation. 217 organisms have orthologs with human gene SLC35G2.