Description: L-Evodiamine is the enantiomer of L-Evodiamine which is a naturally occuring alkaloid extracted from the fruit of Evodiae Fructus, exhibiting antitumor activities against the human tumor cells. Evodiamine induces the substantial amount of apoptosis both in Bcl-2- and Akt-overexpressing U937 cells but not in human peripheral blood mononuclear cells via caspase-independent apoptotic pathways. Evodiamine Evodiamine also inhibits tumor necrosis factor (TNF)-induced NF-kappaB and Akt activation but it has no effect on JNK or p38 MAPK activation.

References: Mol Cancer Ther. 2006 Sep;5(9):2398-407; J Biol Chem. 2005 Apr 29;280(17):17203-12.

纯度：≥98%