CRACR2A抗体

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CRACR2A抗体

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称

Anti-CRACR2A
Anti-calcium release activated channel regulator 2A Antibody

产品介绍

靶标：

CRACR2A

产品别名：

EFCAB4B； RAB46； CRACR2A； calcium release activated channel regulator 2A； calcium release activated channel regulator 2A； EF-hand calcium-binding domain-containing protein 4B； CRAC channel regulator 2A； CRAC regulator 2A； Ca2+ release-activated Ca2+ (CRAC) channel regulator 2A； EF-hand calcium binding domain 4B； calcium release-activated calcium channel regulator 2A； ras-related protein Rab-46；

背景信息：

[Isoform 1]: Ca(2+-binding protein that plays a key role in store-operated Ca(2+ entry (SOCE in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca(2+ concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca(2+ resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex.

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。