靶标:
POLR3C
产品别名:
C82; RPC3; RPC62; POLR3C; RNA polymerase III subunit C; RNA polymerase III subunit C; DNA-directed RNA polymerase III subunit RPC3; DNA-directed III 62 kDa polypeptide; DNA-directed RNA polymerase III subunit C; RNA polymerase III 62 kDa subunit; RNA polymerase III subunit C3; polymerase (RNA) III (DNA directed) polypeptide C (62kD); polymerase (RNA) III subunit C; DNA指导的RNA聚合酶亚基C;
背景信息:
disease:Antibodies against POLR3C were found in the sera of patients with systemic sclerosis (SSc).,function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation.,similarity:Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.,subunit:Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits (By similarity). RPC3/POLR3C, RPC6/POLR3F and RPC7/POLR3G form a Pol III subcomplex. Interacts with GTF3C4.,
宿主:Rbt
类型:Pab
同种型:IgG
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。