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丝裂原活化蛋白激酶8相互作用蛋白1抗体
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
Anti-MAPK8IP1
Anti-mitogen-activated protein kinase 8 interacting protein 1 Antibody
产品介绍
靶标:

MAPK8IP1


产品别名:

IB1; JIP-1; JIP1; PRKM8IP; MAPK8IP1; mitogen-activated protein kinase 8 interacting protein 1; mitogen-activated protein kinase 8 interacting protein 1; C-Jun-amino-terminal kinase-interacting protein 1; IB-1; JNK MAP kinase scaffold protein 1; JNK-interacting protein 1; PRKM8 interacting protein; islet-brain 1; 丝裂原活化蛋白激酶8相互作用蛋白1;


背景信息:
This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes. [provided by RefSeq, May 2011],

宿主:Rbt
类型:Pab
同种型:IgG  
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user           
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。