靶标:
MED23
产品别名:
ARC130; CRSP130; CRSP133; CRSP3; DRIP130; MRT18; SUR-2; SUR2; MED23; mediator complex subunit 23; mediator complex subunit 23; mediator of RNA polymerase II transcription subunit 23; 130 kDa transcriptional co-activator; 133 kDa transcriptional co-activator; activator-recruited cofactor 130 kDa component; cofactor required for Sp1 transcriptional activation subunit 3; vitamin D3 receptor interacting protein; 多巴胺受体相互作用蛋白1; 转录共激活因子130;
背景信息:
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2012],
宿主:Rbt
类型:Pab
同种型:IgG
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。