靶标:
SGPL1
产品别名:
NPHS14; S1PL; SPL; SGPL1; sphingosine-1-phosphate lyase 1; sphingosine-1-phosphate lyase 1; sphingosine-1-phosphate lyase 1; SP-lyase 1; SPL 1; hSPL; sphingosine-1-phosphate aldolase; 磷酸鞘氨醇裂解酶1; 鞘氨醇1磷酸酯裂解酶1(SGPL1);
背景信息:
Cleaves phosphorylated sphingoid bases (PSBs, such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. Required for global lipid homeostasis in liver and cholesterol homeostasis in fibroblasts. Involved in the regulation of pro-inflammatory response and neutrophil trafficking. Modulates neuronal autophagy via phosphoethanolamine production which regulates accumulation of aggregate-prone proteins such as APP (By similarity. Seems to play a role in establishing neuronal contact sites and axonal maintenance (By similarity.
宿主:Rbt
类型:Pab
同种型:IgG
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。