PR5-LL-CM01 is a novel and potent inhibitor of protein arginine methyltransferase 5 (PRMT5) with anticancer activity. It inhibits PRMT5 with IC50 of 7.5 uM, displays >10-fold selectivity over PRMT3, and no inhibitory activity over PRMT1/4/6/8; exhibits cell viability inhibition with IC50 of 2-4 uM in PDAC cells, IC50 of 10-11 uM in CRC cells, more potent than EPZ015666.

纯度：≥98%

CAS：1005307-86-7