靶标：
CXCR2
产品别名：
CD182； CDw128b； CMKAR2； IL8R2； IL8RA； IL8RB； WHIMS2； CXCR2； C-X-C motif chemokine receptor 2； C-X-C motif chemokine receptor 2； C-X-C chemokine receptor type 2； CXC-R2； CXCR-2； CXCR2 gene for IL8 receptor type B； GRO/MGSA receptor； IL-8 receptor type 2； IL-8R B； chemokine (CXC) receptor 2； high affinity interleukin-8 receptor B； interleukin 8 receptor type 2； interleukin 8 receptor, beta； interleukin-8 receptor type B； 白介素8受体β(IL8Rb)； 细胞表面趋化因子受体2；
背景信息：
C-X-C motif chemokine receptor 2(CXCR2) Homo sapiens The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as
宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
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