A fluorescent H2S probe
货号:ajcx19896
CAS:433254-36-5
分子式:C17H10F3NO5
分子量：365.3
溶解度:Chloroform: 30 mg/ml,Chloroform: 30mg/mL,DMF: 30 mg/ml,DMF: 30mg/mL,DMF:PBS (pH 7.2) (1:2): 0.33 mg/ml,DMF:PBS (pH 7.2) (1:2): 30mg/mL,DMSO: 5 mg/ml,DMSO: 5mg/mL
纯度：98%
存储：Store at -20°C
库存：现货

Background:

4-Methyl-7-(4-nitro-2-(trifluoromethyl)phenoxy)-2H-chromen-2-one is a turn-on fluorescent probe for the detection of hydrogen sulfide (H2S).1 It can be excited at 348 nm in DMSO and fluorescence intensity increases in the presence of bisulfide (HS-). 4-Methyl-7-(4-nitro-2-(trifluoromethyl)phenoxy)-2H-chromen-2-one is selective for HS- over cysteine, AcO-, F-, H2PO4-, Cl-, Br-, and I- and is not cytotoxic up to a concentration of 150 μg/ml.

|1. Chen, Y., Shang, X., Li, C., et al. The synthesis, crystal, hydrogen sulfide detection and cell assement of novel chemsensors based on coumarin derivatives. Sci. Rep. 8(1), 16159 (2018).