| 包装: | 1mg |
| 规格: | 98% |
| 市场价: | 891元 |
| 分子量: | 1707.03 |
Background:
Potent apelin (APJ) receptor agonist (Ki = 0.93 nM). Bioactive fragment of ELA-32 . Activates Gαi1 pathway and β-arrestin-2 recruitment. Reduces arterial pressure in rat hearts. Active in vivo. ELA-14 negative control (Cat.No. 6294) also available.
Murza et al (2016) Discovery and structure-activity relationship of a bioactive fragment of ELABELA that modulates vascular and cardiac functions. J.Med.Chem. 59 2962 PMID:26986036
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