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STING Agonist 1a
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
STING Agonist 1a图片
规格:98%
分子量:396.2
包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议
10mg电议

产品介绍
A STING agonist
货号:ajcx23534
CAS:652142-94-4
分子式:C19H11Cl2N5O
分子量:396.2
溶解度:DMF: slightly soluble,DMSO: slightly soluble,PBS (pH 7.2): slightly soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

STING agonist 1a is an agonist of stimulator of interferon genes (STING).1It induces expression of an IRF-inducible SEAP reporter gene in a cell-based assay (EC50= 16.77 µM). STING agonist 1a (12.5-100 µM) induces expression of IFN-β, IL-6, and chemokine (C-X-C motif) ligand 10 (CXCL10) in THP-1 cells, an effect that can be reversed by STING knockout or the STING inhibitor H-151 .


1.Hou, H., Yang, R., Liu, X., et al.Discovery of triazoloquinoxaline as novel STING agonists via structure-based virtual screeningBioorg. Chem.100103958(2020)