您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > AZD 2716
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
AZD 2716
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AZD 2716图片
规格:98%
分子量:373.4
包装与价格:
包装价格(元)
5mg电议
25mg电议

产品介绍
An sPLA2 inhibitor
货号:ajcx26492
CAS:1845753-81-2
分子式:C24H23NO3
分子量:373.4
溶解度:DMF: 16 mg/mL,DMSO: 10 mg/mL,Ethanol: 16 mg/mL,PBS (pH 7.2): 0.3 mg/mL
纯度:98%
存储:Store at -20°C
库存:现货

Background:

AZD 2716 is an inhibitor of secretory phospholipase A2(sPLA2; IC50s = 0.01, 0.04, and 0.4 µM for sPLA2-IIa, -V, and -X, respectively).1It inhibits sPLA2activity in atherosclerotic plaque homogenates isolated from patients with coronary artery disease (IC50= 56 nM).

1.Giordanetto, F., Pettersen, D., Starke, I., et al.Discovery of AZD2716: A novel secreted phospholipase A2 (sPLA2) inhibitor for the treatment of coronary artery diseaseACS Med. Chem. Lett.7(10)884-889(2016)