| 规格: | 98% |
| 分子量: | 510.15 |
| 包装 | 价格(元) |
| 10mg | 电议 |
| 50mg | 电议 |
Background:
KDM4A/KDM4B inhibitor; inhibits histone demethylase activity on H3K9me3 and induces apoptosis in LNCaP prostate cancer cells in vitro. Also negatively regulates androgen-responsive genes.
Chu et al (2014) KDM4B as a target for prostate cancer: structural analysis and selective inhibition by a novel inhibitor. J.Med.Chem. 57 5975 PMID:24971742
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