CAY10789 (compound 6) 是一种有效的 CysLT1R (半胱氨酰白三烯受体 1) 拮抗剂 (IC50=2.80 μM) 和 GPBAR1 (G-蛋白偶联胆汁酸受体 1) 激动剂 (EC50=3 μM)。
货号:ajcx28354
CAS:123226-28-8
分子式:C17H15NO2
分子量：265.3
溶解度:DMF: 11 mg/mL,DMSO: 5 mg/mL,Ethanol: 11 mg/mL,PBS (pH 7.2): 0.14 mg/mL
纯度：98%
存储：Store at -20°C
库存：现货

Background:

CAY10789 is an antagonist of the cysteinyl leukotriene 1 (CysLT₁) receptor (IC₅₀= 2.1 µM).¹

1.Fiorillo, B., Sepe, V., Conflitti, P., et al.Structural basis for developing multitarget compounds acting on cysteinyl leukotriene receptor 1 and G-protein-coupled bile acid receptor 1J. Med. Chem.64(22)16512-16529(2021)