Dapaconazole 作为一种抗真菌化合物，抑制 sterol 14α-demethylase cytochrome P450 活性的 IC50 值为 1.4 μM。
货号:ajcx33458
CAS:1269726-67-1
分子式:C19H15Cl2F3N2O
分子量：415.24
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Dapaconazole, as an antifungal agent, inhibits sterol 14α-demethylase cytochrome P450 activity with an IC50 of 1.4 μM[1].

Dapaconazole inhibits sterol 14α-demethylase cytochrome P450 activity with an IC50 of 1.4 ± 0.3 μM[1].

Dapaconazole (20 mg/kg; p.o.) shows that the bioavailability is 97.3 %[1].

[1]. Juliana SP, et al. Pharmacokinetics of Dapaconazole, A Novel Antifungal Agent, in Beagle Dogs and Inhibition of Cytochrome P450 Family 51. J Eur Acad Dermatol Venereol. 2018 Jun 10.