KMG-104 是一种高选择性荧光 Mg2+ 探针。KMG-104 被广泛应用，并显示 Mg2+ 在各种类型细胞的细胞质中流动情况。
货号:ajcx37198
CAS:852057-94-4
分子式:C23H11F2NO6
分子量：435.33
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

KMG-104 is a highly selective fluorescent Mg2+ probe. KMG-104 has been used widely and revealed Mg2+ mobilization in cytoplasm in various types of cells[1].

KMG-104 is useful for confocal laser scanning microscopy because it is excited at 490 nm, and emitted fluorescence around 510 nm. Fluorescent intensity of KMG-104 increases with [Mg] increase, and it shows no response to Na, K, and Ca; the dissociation constant (Kd) for Mg is 3 mM. KMG-104 is able to trace only [Mg] change inphysiological conditions[2].PC12 cells are loaded with a novel Mg indicator KMG-104 and Ca indicator fura-2, and intracellular Mg is studied in the endoplasmic reticulums (ERs), mitochondria, and Mg-ATP[2].

[1]. Kubota T, et al. Investigation of intracellular magnesium mobilization pathways I PC12 cells B simultaneous Mg-Ca fluorescent imaging. J Am Coll Nutr. 2004;23(6):742S-4S.
[2]. Fujii T, et al. Design and synthesis of a FlAsH-type Mg2+ fluorescent probe for specific protein labeling. J Am Chem Soc. 2014;136(6):2374-2381.