NUCC-390 dihydrochloride 是新型的选择性小分子 CXCR4 receptor 受体激动剂。NUCC-390 dihydrochloride 可以诱导 CXCR4 受体的内化，作用方式与 AMD3100 相反。NUCC-390 dihydrochloride 在动物模型中，有助于神经退行性变后神经功能恢复。
货号:ajcx16886
CAS:N/A
分子式:C23H35Cl2N5O
分子量：468.46
溶解度:DMSO: 250 mg/mL (533.66 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

NUCC-390 dihydrochloride is a novel and selective small-molecule CXCR4 receptor agonist. NUCC-390 dihydrochloride induces internalization of CXCR4 receptors and acts in an opposite way of AMD3100 [1]. NUCC-390 dihydrochloride promotes nerve recovery of function after neurodegeneration in vivo[2].

[1]. Mishra RK, et al. Discovery and characterization of novel small-molecule CXCR4 receptor agonists and antagonists.Sci Rep. 2016 Jul 26;6:30155.