CAS NO: | 855998-67-3 |
规格: | ≥98% |
包装 | 价格(元) |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
250mg | 电议 |
Linaprazan mesylate (also known as AZD0865) is a novel, potent inhibitor of gastric H(+),K(+)-ATPase that inhibit acid formation in vitro with a fast onset of effect. AZD0865 belongs to a new class of acid-suppressing agents with rapid onset of action and potent acid inhibition. It inhibits gastric H(+),K(+)-ATPase by K(+)-competitive binding. In porcine ion-leaky vesicles at pH 7.4, AZD0865 concentration-dependently inhibited K(+)-stimulated H(+),K(+)-ATPase activity (IC(50) 1.0+/-0.2 microM) but was more potent at pH 6.4 (IC(50) 0.13+/-0.01 microM).
纯度:≥98%
CAS:855998-67-3