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Linaprazan mesylate(AZD0865)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:855998-67-3
规格:≥98%
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议
250mg电议

产品介绍

Linaprazan mesylate (also known as AZD0865) is a novel, potent inhibitor of gastric H(+),K(+)-ATPase that inhibit acid formation in vitro with a fast onset of effect. AZD0865 belongs to a new class of acid-suppressing agents with rapid onset of action and potent acid inhibition. It inhibits gastric H(+),K(+)-ATPase by K(+)-competitive binding. In porcine ion-leaky vesicles at pH 7.4, AZD0865 concentration-dependently inhibited K(+)-stimulated H(+),K(+)-ATPase activity (IC(50) 1.0+/-0.2 microM) but was more potent at pH 6.4 (IC(50) 0.13+/-0.01 microM).

纯度:≥98%

CAS:855998-67-3