规格: | 98% |
分子量: | 531.69 |
包装 | 价格(元) |
10mg | 电议 |
50mg | 电议 |
Background:
Dual CBP/p300 and BRD4 bromodomain inhibitor (IC50 values are 0.65 and 1.5 μM for CBP and BRD4 respectively). Downregulates IL-6, IL-1β and IFN-β in macrophages.
Chekler (2015) Transcriptional profiling of a selective CREB binding protein bromodomain inhibitor highlights therapeutic opportunities. Chem.Biol. 22 1588 PMID:26670081