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(±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic Acid
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
(±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic Acid图片
规格:98%
分子量:296.5
包装与价格：
包装价格(元)
25ug电议
50ug电议
100ug电议

产品介绍
An oxylipin gut microbiota metabolite
货号:ajcx28212
CAS:34932-14-4
分子式:C18H32O3
分子量：296.5
溶解度:Ethanol: 1 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

(±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic acid is an oxylipin. It is produced from α-linolenic acid by the gut bacteriaL. plantarum.1(±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic acid prevents increases in mRNA expression of the gene encoding SREBP-1c by the liver X receptor (LXR) agonist T0901317 in HepG2 cells. It reduces LPS-induced increases in nitric oxide (NO) production in RAW 264.7 macrophages when used at a concentration of 10 µM.2

1.Nanthirudjanar, T., Furumoto, H., Zheng, J., et al.Gut microbial fatty acid metabolites reduce triacylglycerol levels in hepatocytesLipids50(11)1093-1102(2015) 2.Yang, H.-E., Li, Y., Nishimura, A., et al.Synthesized enone fatty acids resembling metabolites from gut microbiota suppress macrophage-mediated inflammation in adipocytesMol. Nutr. Food Res.61(10)(2017)